Endocytic capsule sensors for probing cellular internalization.
نویسندگان
چکیده
A new class of polymer capsules with an in-built endocytic pH-coupled fluorescence switch is reported. These capsules display reversible "on/off" fluorescence in response to cellular pH variations. Using this system, the high-throughput quantification between surface-bound and internalized capsules is demonstrated. This system allows a fundamental study of the interaction between nanoengineered materials and biological systems at a cellular level.
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عنوان ژورنال:
- Advanced healthcare materials
دوره 3 10 شماره
صفحات -
تاریخ انتشار 2014